The Effect of Grape Seed Proanthocyanidin Extract in Preventing Amikacin-Induced Nephropathy
نویسندگان
چکیده
منابع مشابه
Protective effect of the grape seed proanthocyanidin extract in a rat model of contrast-induced nephropathy.
AIM Contrast-induced nephropathy (CIN) is a common cause of hospital-acquired acute renal failure. Although it is so common, there has been no approved therapy yet. We aimed to investigate the effect of grape seed proanthocyanidin extract (GSPE) on preventing CIN. MATERIALS AND METHODS 24 rats were divided into four groups as control group, GSPE group, contrast medium (CM) group, and CM+GSPE ...
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15 صفحه اولGrape seed proanthocyanidin extract protects lymphocytes against histone-induced apoptosis
Apoptosis of lymphocytes is associated with immunosuppression and poor prognosis in sepsis. Our previous report showed that histones, nuclear proteins released from damaged or dying cells in sepsis, can mediate lymphocyte apoptosis via mitochondria damage. Grape seed proanthocyanidin extract (GSPE), a natural substance with protective properties against oxidative stress, plays a vital role in c...
متن کاملEffects of Grape Seed Proanthocyanidin Extract on Oxidative Stress Induced by Diabetes in Rat Kidney
Background: This study examined the effect of grape seed proanthocyanidin extract (GSPE) on lipid peroxidation content and activity of tissue antioxidant enzymes, including catalase, superoxide dismutase and glutathione peroxidase in diabetic rats. Methods: Thirty male rats were divided into three groups of 10 rats each: control, diabetic and diabetic groups that received 500 mg/kg GSPE for 6 w...
متن کاملEffects of grape seed proanthocyanidin extract on oxidative stress induced by diabetes in rat kidney.
BACKGROUND This study examined the effect of grape seed proanthocyanidin extract (GSPE) on lipid peroxidation content and activity of tissue antioxidant enzymes, including catalase, superoxide dismutase and glutathione peroxidase in diabetic rats. METHODS Thirty male rats were divided into three groups of 10 rats each: control, diabetic and diabetic groups that received 500 mg/kg GSPE for 6 w...
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ژورنال
عنوان ژورنال: Renal Failure
سال: 2012
ISSN: 0886-022X,1525-6049
DOI: 10.3109/0886022x.2011.643391